Publications:

  1. Fan K*, Gökbağ B*, Tang S, Li S, Huang Y, Wang L, Cheng L, Li L. Synthetic lethal connectivity and graph transformer improve synthetic lethality prediction. Brief Bioinform. 2024 Jul 25;25(5):bbae425. doi: 10.1093/bib/bbae425. PMID: 39210507; PMCID: PMC11361842.
  2. Gökbağ B, Tang S, Fan K, Cheng L, Yu L, Zhao Y, Li L. SLKB: synthetic lethality knowledge base. Nucleic Acids Res. 2024 Jan 5;52(D1):D1418-D1428. doi: 10.1093/nar/gkad806. PMID: 37889037; PMCID: PMC10767912.
  3. Fan K, Tang S, Gökbağ B, Cheng L, Li L. Multi-view graph convolutional network for cancer cell-specific synthetic lethality prediction. Front Genet. 2023 Jan 9;13:1103092. doi: 10.3389/fgene.2022.1103092. PMID: 36699450; PMCID: PMC9868610.
  4. Tang S*, Gökbağ B*, Fan K*, Shao S, Huo Y, Wu X, Cheng L, Li L. Synthetic lethal gene pairs: Experimental approaches and predictive models. Front Genet. 2022 Dec 1;13:961611. doi: 10.3389/fgene.2022.961611. PMID: 36531238; PMCID: PMC9751344.
  5. Tang S, Wu X, Liu J, Zhang Q, Wang X, Shao S, Gökbağ B, Fan K, Liu X, Li F, Cheng L, Li L. Generation of dual-gRNA library for combinatorial CRISPR screening of synthetic lethal gene pairs. STAR Protoc. 2022 Aug 24;3(3):101556. doi: 10.1016/j.xpro.2022.101556. PMID: 36060092; PMCID: PMC9428847.
  6. Cheng L, Karkhanis P, Gökbağ B, Liu Y, Li L. DGCyTOF: Deep learning with graphic cluster visualization to predict cell types of single cell mass cytometry data. PLoS Comput Biol. 2022 Apr 11;18(4):e1008885. doi: 10.1371/journal.pcbi.1008885. PMID: 35404970; PMCID: PMC9060369.
*: Co-First Author

Presentations:

  1. American Association for Cancer Research - Annual Meeting, 2025: TLSL: Transfer learning for synthetic lethality (SL) experiment design and SL prediction
  2. American Association for Cancer Research - Annual Meeting, 2023: SLKB: Synthetic lethality knowledge base for gene combination double knockout experiments
  3. Spring Denman Research Forum at Ohio State University, 2020: Measuring Possible Future Selves: Using Natural Language Processing for Automated Analysis of Posts about Life Concerns
  4. Ohio Supercomputer Center - Statewide User Groups Conference, 2019: Systematic Detection of Enzalutamide Resistance Mechanism in Castration-Resistant Prostate Cancer
  5. The Ohio State University, Wexner Medical Center, 2019: Framework for Analyzing Enzalutamide Detection Mechanism in Castration-Resistant Prostate Cancer

Thesis:

(Ph.D.) Artificial Intelligence Guided Systems Biology for Synthetic Lethality and Gene Combination Effect Prediction: Bridging In Silico and In Vitro. 2025. Thesis link.

(B.S.) Measuring Possible Future Selves: Using Natural Language Processing for Automated Analysis of Posts about Life Concerns. 2020. Thesis link.